Assignment purpose: The focus of this assignment is to solidify an understanding of centromeric DNA (centromere), the kinetochore, unduplicated and duplicated chromosomes, and counting chromosomes during different phases of mitosis.
InstructionsComplete the worksheet provided in the assignment. Embedded media is located in the document.Assignment Chapter 12 The Cell Cycle-2.docxDownload Assignment Chapter 12 The Cell Cycle-2.docx
Attempts are unlimited until the due date.
View the grading rubric.
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Hoffman
Biology 1406 lecture
Worksheet for Mitosis
Building Knowledge
Hover your mouse over the embedded video. Then, select play and YouTube. Pause it to take notes and read about the topics in the textbook chapter and associated lecture highlights.
1. Using the information in the textbook chapter and associated lecture highlights, describe the structure of the centromere of an unduplicated chromosome. Is it a continuous part of the chromosome or a separate structure?
2. Review figure 12.4 in the textbook chapter. Draw a duplicated chromosome, showing two sister chromatids. Label the centromeric region (centromere) of each one.
Hoffman
Biology 1406 lecture
3. Using the information in the textbook chapter and associated lecture highlights, describe the structure and function of the kinetochore. Give the location of each kinetochore relative to the centromere of each sister chromatid.
Application
Use the information in the following statement to answer all parts of the application section.
Statement
The diploid number of chromosomes in the somatic cells of a species of insect is 6 (2n = 6).
1. In each column, draw the six chromosome(s) and label the centromeric region.
Prophase Telophase and cytokinesis completed
2. Complete the chart.
|
Stage of Mitosis |
Number of centromeres per cell |
Number of chromosomes per cell |
Pairs of sister chromatids per cell |
|
Prophase |
|||
|
Telophase |
3. Upon completion of telophase and cytokinesis, has the chromosome number changed? Explain your answer in no more than three sentences.
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